Toxic Bullets
Cost  3,200
Tier 3
Passive
Your bullets build up a Bleed on enemies, causing them to lose a percentage of their Max Health over time. Also applies Healing Reduction on the bleeding target.
  1.9  x0.005%/sec
Bleed Damage
  -35%
Healing Reduction
Conditional
4s Duration
Internal name: upgrade_toxic_bullets
Sounds

Toxic Bullets
Cost  3,200
Tier 3
Enhanced 
Passive
Your bullets build up a Bleed on enemies, causing them to lose a percentage of their Max Health over time. Also applies Healing Reduction on the bleeding target.
  -65%
Healing Reduction
Conditional
4s Duration
Internal name: upgrade_toxic_bullets
Sounds

Toxic Bullets is a Tier 3 Weapon Item that can be purchased from the Shop for Souls3,200.

Notes

  • Bleed damage can kill.
  • The bleed effect is indicated by puddles of blood dropping from the player.
  • Bleed damage applies or "ticks" every half-second, dealing slightly over 1.2% max health spirit damage per tick. This means that, by default, bleed applies damage six times every time it is successfully built up for 7.5% max health spirit damage.
  • Bleed Damage is considered Spirit Damage and is reduced by Spirit Resist.
  • The duration of the bleed is affected by the Ability Duration stat, such as from Superior Duration. The extra damage is applied proportionally. For instance, since Superior Duration adds .84 seconds to the bleed effect, the bleed will deal 2.1% extra spirit damage for a total of 9.6% max health spirit damage.
  • Headshots do not affect the buildup per shot.
  • Light and Heavy Melee attacks count as one full shot each.
  • Bleed does not build on any structures, such as Guardians and Walkers. Mid-boss is also immune to bleed.
  • Bleed does build on Troopers and Denizens, but deals 50% damage.
  • The healing reduction only applies while the target is bleeding.
  • The healing reduction stacks with other sources of healing reduction. For instance,   Healbane and Toxic Bullets will apply a healing reduction effect of 55%.
  • The buildup per shot is also affected by weapon falloff, requiring more shots for the bleed to occur at further distances. Once applied, the bleed damage itself is unaffected by distance.
  • For heroes with spreadshot weapons (  Abrams,   Calico,   Yamato, etc.), the listed bleed buildup applies on a shot where every pellet hits its target. The buildup is divided evenly between each pellet and missing one pellet will proportionally decrease buildup.
  • For characters with burst-fire weapons (  Lash,   Seven, etc.), the listed bleed buildup applies for each bullet rather than each burst. Landing a full burst as Lash, for instance, will build 45.9% of bleed on a target.
  • For characters with splash damage alternate fire weapons (  Viscous and   Yamato), the listed bleed buildup applies in full regardless of whether a target was hit directly or indirectly with a shot.
  •   Shiv's alt-fire builds bleed identically to his primary fire.

Buildup Per Shot

The item has a different buildup per shot depending on which hero purchased the item. The bleed only triggers on an enemy once the buildup reaches 100%, and the buildup decays back to 0 over time if the enemy has not been shot recently. Subsequent shots on a bleeding enemy (bullets or melee) refreshes the duration of the bleed.

Buildup Per Bullet: Toxic Bullets
Hero% per bulletBullets/ShotShots to Proc
(all bullets hit)
  Abrams3.494
  Apollo21.55
  Bebop6.117
  Billy6.117
  Calico1.598
  Celeste28.74
  The Doorman28.74
  Drifter8.035
  Dynamo16.27
  Graves7.214
  Grey Talon29.34
  Haze7.414
  Holliday25.14
  Infernus7.414
  Ivy5.319
  Kelvin16.27
  Lady Geist25.14
  Lash11.49
  McGinnis6.117
  Mina15.77
  Mirage21.05
  Mo & Krill3.149
  Paige22.35
  Paradox9.111
  Pocket3.874
  Rem16.17
  Seven11.49
  Shiv4.664
  Silver5.173
  Silver (Transformed)37.03
  Sinclair21.05
  Venator8.712
  Victor11.49
  Vindicta14.77
  Viscous13.68
  Vyper5.120
  Warden16.27
  Wraith6.715
  Yamato4.655

Update history

View the full update history: Toxic Bullets/Update history

Update Changes

June 30, 2026

  • Bleed damage increased from 1.7% to 1.9%.

May 22, 2026

  • No longer builds up from melee attacks.

April 10, 2026

  • Buildup is now 10% slower.
  • Bleed reduced from 2% to 1.7%.
  • Anti Heal increased from -30% to -35%.
Weapon
Vitality
Spirit